Recently, the Assad forces have managed to gain an upper hand in their fight to gain control of Aleppo which has now almost been encircled. This assault has been supported by russian air strikes that have often indicriminately targeted civilians and while purportedly targetted ISIS, they have notably stuck everyone but ISIS.
Encirclement will allow the Assad regime to carry out their time tested practice of starving the place into submission or death. A detailed map of the city and who controls what is available at this link
The Russian involvement in Syria since september has become a major game changer - the regime, which was on the brink of collapse and losing ground almost daily is currently resurgent.
The unfortunate side efffect of this is that the civilians are even more so in the firing line as Russia does not seem to care about civilian casualties (I am unsure if the Western coalition is - I have not seen many reports of the results of the air strikes).
Up to 70,000 civillians are currently reported to ahve fleed Aleppo and have headed towards Turkey.
In all of the battlegrounds, one striking thing to notice is that any battlegrounds between Assad's forces and ISIS are calm.
ISIS normally kills and decapitates its enemies - unless they are Assad's forces, in which case they are held captive and traded as part of prisoner exchanges.
Recent peace talks collapsed due to the assault on Aleppo and it seems that the US has recently indicated to Assad that they are happy for him to remain in power, which is a reward for the chaos that the Assad regime has put his own people through. It remains to be seen if the people on the ground will willingly accept this or will be forced (through cutting off supplies and arms etc) to accept this, or even if they will continue fighting,
The only solution I can see is one that is unlikely to happen - for Turkey to annex northern Syria and Northern Iraq. Nowt wrong with redrawing the map a little - except that it could lead to World War 3.